Nano Research sets this NR45 award to young researchers in various fields related to nanoscience and nanotechnology, in recognition of their distinguished accomplishments and/or potential to make substantial contributions to their field. For this inaugural year, we highlight 45 innovators in the field of nanobiotechnology, covering research focus of biosensors, imaging, drug delivery and tissue engineering for diagnosing and treating different diseases. All the awardees were invited to submit research or review papers that underwent through a rigorous peer-review process. Nano Research will publish a Special Issue featuring their work shortly. We will announce the selection details of the next NR45 award in the end of this year.