Research Article

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2013, 6(5): 356–364

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https://doi.org/10.1007/s12274-013-0312-z

Redox-sensitive colorimetric polyaniline nanoprobes synthesized by a solvent-shift process

Jihye Choi1,§, Yoochan Hong2,§, Eugene Lee3, Myeong-Hoon Kim1, Dae Sung Yoon2, Jinsuck Suh3,4,5, Yongmin Huh3,4,5, Seungjoo Haam1,4 (), and Jaemoon Yang3,4,6 ()

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1 Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea
2 Department of Biomedical Engineering, Yonsei University, Wonju 220-710, Republic of Korea
3 Department of Radiology, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea
4 YUHS-KRIBB Medical Convergence Research Institute, Seoul 120-752, Republic of Korea
5 Severance Biomedical Science Institute (SBSI), Seoul 120-752, Republic of Korea
6 Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University Health System, Seoul 120-752, Republic of Korea
§ These authors contributed equally to this work

Keywords: polyaniline, solvent-shifting, cancer, colorimetric, nanoprobe
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  • Abstract
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We have synthesized water-stable polyaniline nanoparticles coated with triarmed polyethylene glycol chains using a solvent-shift method and confirmed their colloidal size and aqueous solubility. Furthermore, we have demonstrated that the polyaniline nanoparticles can be doped with biological dopants to produce distinct color changes allowing the detection of live cancer cells.
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Redox-sensitive colorimetric polyaniline nanoprobes synthesized by a solvent-shift process. Nano Res. 2013, 6(5): 356–364 https://doi.org/10.1007/s12274-013-0312-z

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