Review Article


2018, 11(9): 4468–4488


Flexible surface-enhanced Raman scattering-active substrates based on nanofibrous membranes

Ekaterina S. Prikhozhdenko1 (*), Daniil N. Bratashov1, Dmitry A. Gorin1,2, and Alexey M. Yashchenok1,2 (*)

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1 Remote Controlled Theranostic Systems Lab, Education and Research Institute of Nanostructures and Biosystems, Saratov State University, 83 Astrakhanskaya Str., Saratov 410012, Russia
2 Skoltech Center for Photonics and Quantum Materials, Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, 3 Nobel Str., Moscow 143026, Russia

Keywords: paper, electrospun membrane, fabric, surface-enhanced Raman spectroscopy, on-site diagnostics, swabbing
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ABSTRACT Surface-enhanced Raman scattering (SERS) has emerged as an excellent analytical tool for the effective detection and fingerprint identification of various chemicals. Recently, significant progress has been made in the fabrication of SERS-active substrates using simple, inexpensive, and affordable methods. The full potential of universal SERS diagnostics will likely be realized with the development of approaches and devices capable of effectively detecting analytes on various surfaces as well as in multicomponent media. In addition, the combination of implantable or wearable SERS-active substrates and remote portable devices enables real-time diagnostics that ideally fit the concept of personalized medicine. In this paper, we summarize recent achievements in fabricating flexible SERS substrates made of cellulose paper, polymer membranes, and textile fibrous films. Emphasis is placed on the in-situ extraction and detection of various chemicals in real-world surfaces and complex media using flexible nanofibrous SERS platforms. The potential SERS applications and future perspectives in on-site diagnostics are also discussed.
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Flexible surface-enhanced Raman scattering-active substrates based on nanofibrous membranes. Nano Res. 2018, 11(9): 4468–4488

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