Review Article


2020, 13(10): 2595–2616


Nanotechnologies for enhancing cancer immunotherapy

Jingxian Yang, Chunhui Wang, Shuo Shi (*), and Chunyan Dong (*)

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Breast cancer center, Shanghai East Hospital, School of Medicine, Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200120, China

Keywords: cancer immunotherapy, nanoplatform-based technology, combination therapy, synergistic effect
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  • Abstract
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Immunotherapy, a burgeoning field differs from traditional cancer treatments, is revolutionizing oncologic therapeutics. It aims to stimulate the innate and adaptive immune system of a patient to fight against tumor cells. However, low response rate and immune-related adverse effects (irAEs) remain problems during its management. A novel technology using nanomaterials may bring a solution. Various nanoparticles have been investigated as delivery systems to augment cancer therapeutic efficacy in the lab and clinic. In this review, we briefly summarize the connotation of immunotherapy, the application of nanotechnology in cancer, especially focusing on the synergistic effect of nanoplatform-based technology combined with cancer immunotherapy, hoping to make readers a deep insight into this interdisciplinary field.
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Nanotechnologies for enhancing cancer immunotherapy. Nano Res. 2020, 13(10): 2595–2616

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