Research Article


2021, 14(4): 920–933


Recent advances in engineered nanomaterials for acute kidney injury theranostics

Lefeng Wang1,2, Yunjing Zhang3, Yangyang Li4 (✉), Jianghua Chen1,2 (✉), and Weiqiang Lin3 (✉)

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1 Kidney Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Nephrology, Zhejiang University, Hangzhou 310003, China
2 Key Laboratory of Kidney Disease Prevention and Control Technology, Hangzhou 310003, China
3 The Fourth Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Jinhua 322000, China
4 Key Laboratory of Women’s Reproductive Health Research of Zhejiang Province, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China

Keywords: acute kidney injury, nanomaterials, early detection, therapy, translational applications
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  • Abstract
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Acute kidney injury (AKI), has become the focus of increasing attention due to its high risk of death. The early diagnosis and treatment of AKI significantly reduce the risk of renal tissue damage and kidney dysfunction. However, the efficient early diagnosis and treatment approach for AKI remains a challenge. AKI screening via precise nanomaterial theranostics is a new alternative approach. This study summarizes the recent advances in functional nanomaterials in the early detection and treatment of AKI. The challenges and problems in the use of nanomaterials for AKI in clinical applications are also discussed. It is anticipated that highlighting these new advances will lay the foundation for further translational research on the promising application of nanomaterials for AKI.
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Recent advances in engineered nanomaterials for acute kidney injury theranostics. Nano Res. 2021, 14(4): 920–933

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