Review Article


2021, 14(3): 570–583


Carbon-based nanozymes for biomedical applications

Hui Ding1, Bing Hu1, Bin Zhang1, Han Zhang3, Xiyun Yan4 (✉), Guohui Nie1 (✉), and Minmin Liang2 (✉)

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1 Department of Otolaryngology and Institute of Translational Medicine, Shenzhen Second People’s Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen 518035, China
2 Experimental Center of Advanced Materials, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China
3 SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology, and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China
4 Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

Keywords: nanozymes, carbon nanomaterials, carbon nanozymes, enzyme-like activity
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  • Abstract
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Nanozymes are nanomaterials with enzyme-like properties that have attracted significant interest owing to their capability to address the limitations of traditional enzymes such as fragility, high cost, and impossible mass production. Over the past decade, a broad variety of nanomaterials have been found to mimic the enzyme-like activity by engineering the active centers of natural enzymes or developing multivalent elements within nanostructures. Carbon nanomaterials with well-defined electronic and geometric structures have served as favorable surrogates of traditional enzymes by mimicking the highly evolved catalytic center of natural enzymes. In particular, by combining the unique electronic, optical, thermal, and mechanical properties, carbon nanomaterials-based nanozymes can offer a variety of multifunctional platforms for biomedical applications. In this review, we will introduce the enzymatic characteristics and recent advances of carbon nanozymes, and summarize their significant applications in biomedicine.
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Carbon-based nanozymes for biomedical applications. Nano Res. 2021, 14(3): 570–583

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