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Synthesis of Protein Nano-Conjugates for Cancer Therapy

Jianjun Zhang1, Juanjuan Du1, Ming Yan1, Anandika Dhaliwal2, Jing Wen1, Fengqi Liu3, Tatiana Segura1,2 (), and Yunfeng Lu1 ()


1 Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, Los Angeles, CA 90095, USA
2 Biomedical Engineering Interdepartmental Program, University of California at Los Angeles, Los Angeles, CA 90095, USA
3 College of Chemistry, Jilin University, Changchun 130012, China

DOI 10.1007/s12274-011-0098-9

Nano Res. 2011, 4(5): 425每433

Address correspondence to Tatiana Segura, tsegura@ucla.edu; Yunfeng Lu, luucla@ucla.edu

Nano-conjugates of bovine pancreatic ribonuclease A (RNase) have been synthesized using in situ atom transfer radical polymerization (ATRP). Compared with native RNase, such nano-conjugates exhibited enhanced delivery efficiency, inhibitor resistance and cytotoxicity for cancer cells. This work provides a novel platform for delivery of therapeutic proteins for cancers therapeutics and other applications.

    

High-Quality Single-Layer Graphene via Reparative Reduction of Graphene Oxide

Boya Dai1, Lei Fu1(), Lei Liao1, Nan Liu1, Kai Yan1, Yongsheng Chen2, and Zhongfan Liu1()
 
1 Center for Nanochemistry, Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China
2 College of Chemistry, Nankai University, Tianjin, 300071, China

DOI 10.1007/s12274-011-0099-8

Nano Res. 2011, 4(5): 434每439

Address correspondence to L. Fu, leifu@pku.edu.cn; Z. F. Liu, zfliu@pku.edu.cn

Reparative reduction of graphene oxide to obtain high-quality graphene films has been achieved by introducing carbon radicals during the thermal annealing process to eliminate lattice defects. Sheet conductivity of the reparatively reduced single-layer graphene films was significantly increased compared with thermally annealed films. The number of C每C bonds also increased after reparative reduction, indicating the restoration of graphene*s aromatic structure.

    

Selective Growth of ZnO Nanorods on SiO2/Si Substrates Using a Graphene Buffer Layer

Won Mook Choi1,∫, Kyung-Sik Shin2,∫, Hyo Sug Lee1, Dukhyun Choi3, Kihong Kim1, Hyeon-Jin Shin1, Seon-Mi Yoon1, Jae-Young Choi1 (), and Sang-Woo Kim2 ()


1 Samsung Advanced Institute of Technology, Giheung, Yongin, Gyeonggi 446-712, Republic of Korea
2 School of Advanced Materials Science and Engineering, Sungkyunkwan (SKKU) Advanced Institute of Nanotechnology (SAINT), Center for Human Interface Nanotechnology (HINT), Sungkyunkwan University, Suwon 440-746, Republic of Korea
3 Department of Mechanical Engineering, Kyung Hee University, Yongin, Gyeonggi 446-701, Republic of Korea

These authors contributed equally to this work

DOI 10.1007/s12274-011-0100-6

Nano Res. 2011, 4(5): 440每447

Address correspondence to Sangwoo Kim, kimsw1@skku.edu; Jaeyoung Choi, jaeyoung88.choi@samsung.com

ZnO nanorods have been selectively grown mask-free on SiO2/Si substrates using a graphene buffer layer in a low temperature solution process. The nanostructure of ZnO每graphene materials have promising applications in future flexible electronic and optical devices.

    

Synthesis and Enhanced Photocatalytic Activity of Regularly Shaped Cu2O Nanowire Polyhedra

Jing Shi, Jin Li, Xiaojian Huang, and Yiwei Tan ()
 
State Key Laboratory of Materials-Oriented Chemical Engineering, School of Chemistry and Chemical Engineering, Nanjing University of Technology, Nanjing 210009, China

DOI 10.1007/s12274-011-0101-5

Nano Res. 2011, 4(5): 448每459

Address correspondence to ytan@njut.edu.cn

A series of unique nanowire superstructures, Cu2O nanowire poly- hedra, have been synthesized through a cost-effective hydrothermal route. The Cu2O nanowire octahedra exhibit excellent photocatalytic activities for dye degradation under visible light irradiation.

    

Synthesis of Ordered Multivalent Mn每TiO2 Nanospheres with Tunable Size: A High Performance Visible-Light Photocatalyst

Haiyan Li1, Dejun Wang1, Haimei Fan1, Tengfei Jiang1, Xinglin Li2 (), and Tengfeng Xie1 ()


1 State Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry, Jilin University, Changchun 130023, China
2 National Centre for Electrochemical and Spectral Analysis, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

DOI 10.1007/s12274-011-0102-4

Nano Res. 2011, 4(5): 460每469

Address correspondence to Tengfeng Xie, xietf@jlu.edu.cn; Xinglin Li, lxl@ciac.jl.cn

Surface photocurrent measurements reveal that the electronic interaction between Mn and TiO2, in which Mn serves as an electron acceptor and effectively inhibits the charge recombination in TiO2, results in a highly efficient photocatalytic activity for the degradation of rhodamine B under visible-light irradiation ( > 420 nm).

    

Generation and Photocatalytic Activities of Bi@Bi2O3 Microspheres

Xiangwen Liu, Huaqiang Cao(), and Jiefu Yin
 
Department of Chemistry, Tsinghua University, Beijing 100084, China

DOI 10.1007/s12274-011-0103-3

Nano Res. 2011, 4(5): 470每482

Address correspondence to hqcao@mail.tsinghua.edu.cn

Bi@Bi2O3 microspheres have been synthesized via a microwave- assisted solvothermal route without adding any surfactants. The degradation of rhodamine B and methyl orange reached ~96.6% and 100%, respectively, after 4 h reaction in the presence of the as-synthesized Bi@Bi2O3 microspheres.

    

M13 Bacteriophage每Polymer Nanoassemblies as Drug Delivery Vehicles

Nisaraporn Suthiwangcharoen1, Tao Li1, Kai Li1, Preston Thompson1, Shaojin You2 (), and Qian Wang1 ()


1 Department of Chemistry and Biochemistry and Nanocenter, University of South Carolina Columbia, SC 29208, USA
2 Histo-Pathology Core, Atlanta VA Medical Center, 1670 Clairmont Road, Decatur, GA 30033, USA

DOI 10.1007/s12274-011-0104-2

Nano Res. 2011, 4(5): 483每493

Address correspondence to Qian Wang, wang@mail.chem.sc.edu; Shaojin You, shaojin.you@va.gov

A new way to fabricate nanosized targeted drug delivery carriers is demonstrated using chemically modified bacteriophage M13 and a biodegradable polymer. This approach provides a simple and straightforward method to deliver hydrophobic drugs to tumor cells with high selectivity.

    

Synthesis of Monodisperse CexZr1-xO2 Nanocrystals and the Size-Dependent Enhancement of Their Properties

Yuewei Zhang1,2, Jing Wen1,2, Jun Wang1, Daocheng Pan2, Meiqing
Shen1 (), and Yunfeng Lu2 ()
 
1 Key Laboratory for Green Chemical Technology of State Education Ministry, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China
2 Department of Chemical & Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA

DOI 10.1007/s12274-011-0105-1

Nano Res. 2011, 4(5): 494每504

Address correspondence to Meiqing Shen, mqshen@tju.edu.cn; Yunfeng Lu, luucla@ucla.edu

Monodisperse Ce1-xZrxO2 nanocrystals with controlled composition, size and structure have been synthesized using a simple two-phase approach. Size-dependent enhancement of oxygen-storage capacity and kinetics of oxygen storage and release were observed.

    

Electrochemical Performance and ex situ Analysis of ZnMn2O4 Nanowires as Anode Materials for Lithium Rechargeable Batteries

Sung-Wook Kim1,∫, Hyun-Wook Lee2,∫, Pandurangan Muralidharan2,∫, Dong-Hwa Seo2, Won-Sub Yoon3, Do Kyung Kim2 (), and Kisuk Kang2,4 ()


1 Research Institute of Advanced Materials, Seoul National University, 599 Kwanak-ro, Kwanak-gu, Seoul 151-742, Republic of Korea
2 Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, 335 Gwahangno, Yuseong-gu, Daejeon 305-701, Republic of Korea
3 School of Advanced Materials Engineering, Kookmin University, 861-6 Jeongneung-dong, Seongbuk-gu, Seoul 136-702, Republic of Korea
4 Department of Materials Science and Engineering, Seoul National University, 599 Kwanak-ro, Kwanak-gu, Seoul 151-742, Republic of Korea
These authors contributed equally to this work

DOI 10.1007/s12274-011-0106-0

Nano Res. 2011, 4(5): 505每510

Address correspondence to Do Kyung Kim, dkkim@kaist.ac.kr; Kisuk Kang, matlgen1@snu.ac.kr

Highly crystalline ZnMn2O4 nanowires with a uniform size and widths of ca. 15 nm and lengths of 500 nm have been synthesized by a simple synthesis route and shown to be high performance anode materials for Li rechargeable batteries.

    

High Temperature Stability of Platinum Nanoparticles on Few-Layer Graphene Investigated by In Situ High Resolution Transmission Electron Microscopy

Izabela Janowska1(), Maria-Simona Moldovan2, Ovidiu Ersen2, Herv谷 Bulou2, Kambiz Chizari1, Marc J. Ledoux1, and Cuong Pham-Huu1
 
1 Laboratoire des Mat谷riaux, Surfaces et Proc谷d谷s pour la Catalyse (LMSPC, UMR 7515 CNRS), 25, rue Becquerel, F-67087 Strasbourg Cedex 02, France
2 Institut de Physique et Chimie des Mat谷riaux de Strasbourg (IPCMS, UMR 7504 CNRS), 23, rue du Loess, F-67037 Strasbourg Cedex 08, France

DOI 10.1007/s12274-011-0107-z

Nano Res. 2011, 4(5): 511每521

Address correspondence to janowskai@unistra.fr

The thermal stability of platinum nanoparticles on few-layer graphene (FLG) surfaces has been studied by in situ high temperature transmission electron microscopy.

    

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