Volume 14

Issue 01,2021

(41 articles)

Contents(PDF)

Andrea Spitaleri1,2,§, Denis Garoli3,4,§, Moritz Schütte5, Hans Lehrach5,6, Walter Rocchia1 (✉), and Francesco De Angelis3 (✉)

In this work, we introduce the concept of “adaptive nanopore” as the foundation for a novel class of protein sequencing devices. In the proposed approach the nanopore is realized by an engineered protein construct that adapts to the sequence of the translocating polypeptide due to the same molecular forces involved in bio-molecular recognition.
https://doi.org/10.1007/s12274-020-3095-z
2021, 14(1): 328–333
Published: 30 September 2020